Key Publications
1. Codarri, L, Gyülveszi, G. Magnenat, L., Hesske, L., Fontana, A., Suter, T., and Becher, B. (2011) RORγt-dependent GM-CSF secretion by TH cells is essential for the effector phase of EAE pathogenesis. Nature Immunol. 12:560-7.
2. Eisenring, M., Vom Berg, J., Kristiansen, G., Saller, E. and Becher, B. 2010 IL-12 initiates tumor rejection via lymphoid tissue-inducer cells bearing the natural cytotoxici- ty receptor NKp46. Nature Immunol. 11:1030-8.
3. Greter, M., Hofmann, J. and Becher, B. 2009 Extra-lymphoid aggregates in the adult liver can initiate cell-mediated immunity. PLOS-Biology 5:e1000109.
4. Haak, S., Croxford, A., Kreymborg, K., Heppner, F.L., Pouly, S. Waisman, A* and Becher, B.* 2009 IL-17A and IL-17F do not contribute vitally to autoimmune neuro-inflammation. J.Clin.Invest ;119:61-69 ;
5. Gutcher, I., Urich, E., Prinz, M., and Becher, B. 2006 IL-18 independent IL-18R α;engagement induces the generation of encephalopathogenic T cells in vivo. Nature Immunol. 7:946–953.
6. Prinz, M., Garbe, F., Schmidt, H., Mildner, A., Pische, M., Schroers, R., Weiss, E., Gutcher, I., Kirschning, C. J., Rochford, C., Bruck, W., and Becher, B. 2006 TLR-signa- ling by CNS-resident cells modulates T cell encephalitogenicity during the effector phase of EAE J Clin Invest. 116:456–64.
7. Urich, E., Gutcher, I., Prinz, M., and Becher, B. 2006 Autoantibody-mediated demyelination is dependent on complement activation but not activatory Fc-receptors. Proc. Nat. Acad. Sci. 103:18697–702.
8. Greter, M., Heppner, F, Lemos, M.P., Odermatt, B.M., Goebels, N., Laufer, T., Noelle, R.J., and Becher, B. 2005 Dendritic cells permit immune invasion of the CNS during experimental autoimmune encephalomyelitis. Nature Med. 11:328–334.
9. Becher, B., Durell, B.G. and Noelle, R.J. 2002 Experimental autoimmune ence- phalitis and inflammation in the absence of interleukin-12. J. Clin. Invest. 110:493–497.
10. Becher, B., Durell, B.G, Miga, A.V., Hickey, W.F. and Noelle, R.J. 2001 The cli- nical course of experimental autoimmune encephalomyelitis and inflammation is con- trolled by the expression of CD40 within the central nervous system. J. Exp. Med 193:967–974. 15.6.