Key Publications

Panetti C, Kao KC, Joller N‡
Dampening antiviral immunity can protect the host.
FEBS J. 2021 Feb 11.

Estrada Brull A, Rost F, Oderbolz J, Kirchner F, Leibundgut-Landmann S, Oxenius A, Joller N‡
CD85k Contributes to Regulatory T Cell Function in Chronic Viral Infections.
Int J Mol Sci. 2020 Dec 22;22(1):31.

Joller N
Type 1 Treg cells act as unexpected helpers.
Nat Immunol. 2020 Jul;21(7):720-721.

Rost F, Lambert K, Rakebrandt N, Joller N‡
Memory of Viral Infection in Regulatory T cells.
Scientific Reports, 2020 May 20;10(1):8350

Schorer M, Lambert K, Rakebrandt N, Rost F, Kao KC, Yermanos A, Spörri A, Oderbolz J, Raeber ME, Keller CW, Lünemann JD, Rogler G, Boyman O, Oxenius A, Joller N
Rapid expansion of Treg cells protects from collateral colitis following a viral trigger.
Nat Commun.  2020 Mar 24; 11.

Schorer M, Rakebrandt N, Lambert K, Hunziker A, Pallmer K, Oxenius A, Kipar A, Stertz S, Joller N
TIGIT limits immune pathology during viral infections.
Nat Commun. 2020 Mar 9;11(1):1288.

Schorer M, Kuchroo VK, Joller N
Role of Co-stimulatory Molecules in T Helper Cell Differentiation
Adv Exp Med Biol. 2019;1189:153-177.

Rakebrandt N, Joller N
Infection History Determines Susceptibility to Unrelated Diseases.
Bioessays. 2019 Jun;41(6):e1800191

Sparber F, De Gregorio C, Steckholzer S, Ferreira FM, Dolowschiak T, Ruchti F, Kirchner FR, Mertens S, Prinz I, Joller N, Buch T, Glatz M, Sallusto F, LeibundGut-Landmann S.
The Skin Commensal Yeast Malassezia Triggers a Type 17 Response that Coordinates Anti-fungal Immunity and Exacerbates Skin Inflammation.
Cell Host & Microbe, 2019 Mar 13;25(3):389-403.e6.

Barnstorf I, Borsa M, Baumann N, Pallmer K, Yermanos A, Joller N, Spörri R, Welten SPM, Kräutler NJ, Oxenius A.
Chronic virus infection compromises memory bystander T cell function in an IL-6/STAT1-dependent manner.
Journal of Experimental Medicine, 2019 Mar 4;216(3):571-586.

Kirchner FR, Littringer K, Altmeier S, Tran VDT, Schönherr F, Lemberg C, Pagni M, Sanglard D, Joller N, LeibundGut-Landmann S.
Persistence of Candida albicans in the Oral Mucosa Induces a Curbed Inflammatory Host Response That Is Independent of Immunosuppression.
Frontiers in Immunology, 2019 Feb 27;10:330.

Littringer K, Moresi C, Rakebrandt N, Zhou X, Schorer M, Dolowschiak T, Kirchner F, Rost F, Keller CW, McHugh D, LeibundGut-Landmann S, Robinson MD, Joller N
Common features of regulatory T cell specialization during Th1 responses.
Frontiers in Immunology, 2018 Jun 13; 9:1344.

Sparber F, Dolowschiak T, Mertens S, Lauener L, Clausen B, Stoitzner P, Joller N, Tussiwand R, LeibundGut-Landmann S
Langerin+ DCs regulate innate IL-17 production in the oral mucosa during Candia albicans-mediated infection.
PLoS Pathogens, 2018 May 21;14(5):e1007069.

Dixon K*, Schorer M*, Nevin J, Etminan Y, Amoozgar Z, Kondo T, Kurtulus S, Kassam N, Fukumura D, Jain RK, Anderson AC, Kuchroo VK*, Joller N*
Functional anti-TIGIT antibodies regulate development of autoimmunity and anti-tumor immunity.
Journal of Immunology, 2018 Apr 15;200(8):3000-3007.
****Among the top 5 downloaded papers in JI in 2018!****

Joller N, Kuchroo VK
Tim-3, Lag-3, and TIGIT.
Current Topics in Microbiology and Immunology, 2017;410:127-156

Kishi Y, Kondo T, Wang C, Wu C, Yosef N, Regev A, Joller N*, Kuchroo VK*
Protein C receptor (PROCR) regulates the pathogenic phenotype of Th17 cells.
Journal of Experimental Medicine, 2016 Oct 17;213(11):2489-2501.

Rakebrandt N, Littringer K, Joller N
Regulatory T cells: balancing protection vs. pathology.
Swiss Medical Weekly, 2016;146:w14343

Anderson AC, Joller N, Kuchroo VK
Lag-3, Tim-3, and TIGIT co-inhibitory receptors with specialized functions in immune regulation.
Immunity, 2016 May 17;44(5):989-1004

Joller N, Lozano E, Burkett PR, Patel B, Xiao S, Zhu C, Xia J, Tan TG, Sefik E, Yajnik V, Sharpe AH, Quintana FJ, Mathis D, Benoist C, Hafler DA, Kuchroo VK.
Treg cells expressing the coinhibitory molecule TIGIT selectively inhibit proinflammatory Th1 and Th17 cell responses.
Immunity, 2014 Apr 17;40(4):569-81.

Joller N, Kuchroo VK
Good guys gone bad: exTreg cells promote autoimmune arthritis.
Nature Medicine (News and Views), 2014 Jan 7;20(1):15-7

Lozano E, Joller N, Coa Y, Kuchroo VK, Hafler DA
The CD226/CD155 Interaction Regulates the Proinflammatory (Th1/Th17)/Anti-Inflammatory (Th2) Balance in Humans.
Journal of Immunology, 2013 Oct 1;191(7):3673-80

Joller N, Peters A, Anderson AC, Kuchroo VK
Immune checkpoints in central nervous system autoimmunity.
Immunological Reviews, 2012 Jul;248(1):122-39

Weber SS*, Joller N*, Küntzel AB, Spörri R, Tchang VS, Scandella E, Rösli C, Ludewig B, Hilbi H, Oxenius A
Identification of protective B cell antigens of Legionella pneumophila.
Journal of Immunology, 2012 Jul 15;189(2):841-9
* These authors contributed equally

Joller N, Weber SS, Oxenius A
Antibody - Fc receptor interactions in protection against intracellular pathogens.
European Journal of Immunology, 2011 Apr;41(4):889-97.

Joller N, Hafler JP, Brynedal B, Kassam N, Spoerl S, Levin SD, Sharpe AH, Kuchroo VK
Cutting edge: TIGIT has T cell-intrinsic inhibitory functions.
Journal of Immunology (Cutting Edge), 2011 Feb 1;186(3):1338-42.

Joller N*, Weber SS*, Müller AJ, Spörri R, Selchow P, Sander P, Hilbi H, Oxenius A
Antibodies protect against intracellular bacteria by Fc receptor-mediated lysosomal targeting‡.
Proceedings of the National Academy of Sciences USA (PNAS), 2010 Nov 23;107(47):20441-6.
* These authors contributed equally
****Awarded with the Pfizer Research Award 2012!****

Joller N, Spörri R, Hilbi H and Oxenius A
Induction and protective role of antibodies in Legionella pneumophila infection.
European Journal of Immunology, 2007. 37: 3414-3423.


Full Publication List (PDF, 82 KB)