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Institute of Experimental Immunology Inflammation Research

10 Recent original Publications:

  1. Andreadou, Myrto et al. “IL-12 sensing in neurons induces neuroprotective CNS tissue adaptation and attenuates neuroinflammation in mice.” Nature neuroscience , vol. 26,10 (2023): 1701-1712, doi:10.1038/s41593-023-01435-z
  2. Nuñez, Nicolás Gonzalo et al. “High-dimensional analysis of 16 SARS-CoV-2 vaccine combinations reveals lymphocyte signatures correlating with immunogenicity.” Nature immunology , vol. 24,6 (2023): 941-954, doi:10.1038/s41590-023-01499-w
  3. Ingelfinger, Florian et al. “Antibodies Produced by CLL Phenotype B Cells in Patients With Myasthenia Gravis Are Not Directed Against Neuromuscular Endplates.” Neurology(R) neuroimmunology & neuroinflammation , vol. 10,2 e200087. 8 Feb. 2023, doi:10.1212/NXI.0000000000200087
  4. Ingelfinger, Florian et al. “Azathioprine therapy induces selective NK cell depletion and IFN-γ deficiency predisposing to herpesvirus reactivation.” The Journal of allergy and clinical immunology, S0091-6749(22)01187-3. 16 Sep. 2022, doi:10.1016/j.jaci.2022.09.010
  5. Kreutmair, Stefanie et al. “Preexisting comorbidities shape the immune response associated with severe COVID-19.” The Journal of allergy and clinical immunology, vol. 150,2 (2022): 312-324,
  6. Ingelfinger, Florian et al. “Twin study reveals non-heritable immune perturbations in multiple sclerosis.” Nature, 10.1038/s41586-022-04419-4. 16 Feb. 2022.
  7. Amorim, Ana et al. “IFNγ and GM-CSF control complementary differentiation programs in the monocyte-to-phagocyte transition during neuroinflammation.” Nature immunology vol. 23,2 (2022): 217-228.
  8. Krishnarajah, Sinduya et al. Single-cell profiling of immune system alterations in lymphoid, barrier and solid tissues in aged mice Nature Aging (2021).
  9. Zwicky, Pascale et al. “IL-12 regulates type 3 immunity through interfollicular keratinocytes in psoriasiform inflammation.” Science immunology vol. 6,64 (2021): eabg9012.
  10. Kreutmair, Stefanie et al. “Distinct immunological signatures discriminate severe COVID-19 from non-SARS-CoV-2-driven critical pneumonia.” Immunity vol. 54,7 (2021): 1578-1593.e5

Selected Reviews:

  1. Mundt S, Greter M, Becher B. The CNS mononuclear phagocyte system in health and disease. Neuron. 2022;110(21):3497-3512.
  2. Ingelfinger F, Beltrán E, Gerdes LA, Becher B. Single-cell multiomics in neuroinflammation. Curr Opin Immunol. 2022;76:102180. doi:10.1016/j.coi.2022.102180
  3. Krishnarajah S, Becher B. TH Cells and Cytokines in Encephalitogenic Disorders. Front Immunol. 2022;13:822919. Published 2022 Mar 7. doi:10.3389/fimmu.2022.822919
  4. Kreutmair S, Becher B. Response to Are NKT cells a useful predictor of COVID-19 severity?. Immunity. 2022;55(2):188-189. doi:10.1016/j.immuni.2022.01.012
  5. Ingelfinger, Florian et al. GM-CSF: Master regulator of the T cell-phagocyte interface during inflammation. Science direct Volume 54, April 2021, 101518
  6. Tuzlak, Selma et al. Repositioning TH cell polarization from single cytokines to complex help. Nature immunology vol. 22,10 (2021): 1210-1217.
  7. Becher, B. et al. Skipping adolescence to become super-inflammatory monocytes. Nat Immunol. 21(5):491-492 (2020).
  8. Zwicky, P., Unger, S. & Becher, B. Targeting interleukin-17 in chronic inflammatory disease: A clinical perspective. J. Exp. Med. 217, (2020).
  9. Becher, B., Waisman, A. & Lu, L. F. Cre-lox: Target Sensitivity Matters. Immunity vol. 51 595 (2019).
  10. Mundt, S., Greter, M., Flügel, A. & Becher, B. The CNS Immune Landscape from the Viewpoint of a T Cell. Trends in Neurosciences vol. 42 667–679 (2019).

Weiterführende Informationen



You will find an up-to-date list of our publications on the PubMed website.