10 Recent original Publications:

  1. Ingelfinger et al. Single-cell profiling of myasthenia gravis identifies a pathogenic T cell signature. Acta Neuropathol (Mar 28, 2021).
  1. Agliard, Liuzzi et al. Intratumoral IL-12 delivery empowers CAR-T cell immunotherapy in a pre-clinical model of glioblastoma. Nat Commun Jan 19;12(1):444 (2021).
  1. Friebel, E. et al. Single-Cell Mapping of Human Brain Cancer Reveals Tumor-Specific Instruction of Tissue-Invading Leukocytes. Cell. 181(7):1626-1642.e20 (2020).
  1. Galli, E. et al. GM-CSF and CXCR4 define a T helper cell signature in multiple sclerosis. Nat. Med. 25, 1290–1300 (2019).
  1. Komuczki, J. et al. Fate-Mapping of GM-CSF Expression Identifies a Discrete Subset of Inflammation-Driving T Helper Cells Regulated by Cytokines IL-23 and IL-1β. Immunity 50, 1289-1304.e6 (2019).
  1. Mundt, S. et al. Conventional DCs sample and present myelin antigens in the healthy CNS and allow parenchymal T cell entry to initiate neuroinflammation. Sci. Immunol. 4, (2019).
  1. Hartwig, T. et al. Regulatory T Cells Restrain Pathogenic T Helper Cells during Skin Inflammation. Cell Rep. 25, 3564-3572.e4 (2018).
  1. Tugues, S. et al. Graft-versus-host disease, but not graft-versus-leukemia immunity, is mediated by GM-CSF-licensed myeloid cells. Sci. Transl. Med. 10, (2018).
  1. Mrdjen, D. et al. High-Dimensional Single-Cell Mapping of Central Nervous System Immune Cells Reveals Distinct Myeloid Subsets in Health, Aging, and Disease. Immunity 48, 380-395.e6 (2018).
  1. Krieg, C. et al. High-dimensional single-cell analysis predicts response to anti-PD-1 immunotherapy. Nat. Med. 24, 144–153 (2018).

Selected Reviews:

  1. Becher, B. et al. Skipping adolescence to become super-inflammatory monocytes. Nat Immunol. 21(5):491-492 (2020).
  1. Zwicky, P., Unger, S. & Becher, B. Targeting interleukin-17 in chronic inflammatory disease: A clinical perspective. J. Exp. Med. 217, (2020).
  1. Becher, B., Waisman, A. & Lu, L. F. Cre-lox: Target Sensitivity Matters. Immunity vol. 51 595 (2019).
  1. Mundt, S., Greter, M., Flügel, A. & Becher, B. The CNS Immune Landscape from the Viewpoint of a T Cell. Trends in Neurosciences vol. 42 667–679 (2019).
  1. Tugues, S., Ducimetiere, L., Friebel, E. & Becher, B. Innate lymphoid cells as regulators of the tumor microenvironment. Seminars in Immunology vol. 41 101270 (2019).
  1. Galli, E. et al. The end of omics? High dimensional single cell analysis in precision medicine. European Journal of Immunology vol. 49 212–220 (2019).
  1. Becher, B., Waisman, A. & Lu, L. F. Conditional Gene-Targeting in Mice: Problems and Solutions. Immunity 48, 835–836 (2018).
  1. Becher, B., Spath, S. & Goverman, J. Cytokine networks in neuroinflammation. Nature Reviews Immunology vol. 17 49–59 (2017).
  1. Becher, B., Tugues, S. & Greter, M. GM-CSF: From Growth Factor to Central Mediator of Tissue Inflammation. Immunity vol. 45 963–973 (2016).
  1. Mair, F. et al. The end of gating? An introduction to automated analysis of high dimensional cytometry data. Eur. J. Immunol. 46, 34–43 (2016).