10 Recent original Publications:

  1. Ingelfinger, Florian et al. “Twin study reveals non-heritable immune perturbations in multiple sclerosis.” Nature, 10.1038/s41586-022-04419-4. 16 Feb. 2022.
  1. Amorim, Ana et al. “IFNγ and GM-CSF control complementary differentiation programs in the monocyte-to-phagocyte transition during neuroinflammation.” Nature immunology vol. 23,2 (2022): 217-228.
  1. Krishnarajah, Sinduya et al. Single-cell profiling of immune system alterations in lymphoid, barrier and solid tissues in aged mice Nature Aging (2021).
  1. Zwicky, Pascale et al. “IL-12 regulates type 3 immunity through interfollicular keratinocytes in psoriasiform inflammation.” Science immunology vol. 6,64 (2021): eabg9012.
  1. Kreutmair, Stefanie et al. “Distinct immunological signatures discriminate severe COVID-19 from non-SARS-CoV-2-driven critical pneumonia.” Immunity vol. 54,7 (2021): 1578-1593.e5
  1. Ingelfinger et al. Single-cell profiling of myasthenia gravis identifies a pathogenic T cell signature. Acta Neuropathol (Mar 28, 2021).
  1. Agliard, Liuzzi et al. Intratumoral IL-12 delivery empowers CAR-T cell immunotherapy in a pre-clinical model of glioblastoma. Nat Commun Jan 19;12(1):444 (2021).
  1. Friebel, E. et al. Single-Cell Mapping of Human Brain Cancer Reveals Tumor-Specific Instruction of Tissue-Invading Leukocytes. Cell. 181(7):1626-1642.e20 (2020).
  1. Galli, E. et al. GM-CSF and CXCR4 define a T helper cell signature in multiple sclerosis. Nat. Med. 25, 1290–1300 (2019).
  1. Komuczki, J. et al. Fate-Mapping of GM-CSF Expression Identifies a Discrete Subset of Inflammation-Driving T Helper Cells Regulated by Cytokines IL-23 and IL-1β. Immunity 50, 1289-1304.e6 (2019).

Selected Reviews:

  1. Sinduya Krishnarajah, Burkhard Becher. TH Cells and Cytokines in Encephalitogenic Disorders Frontiers in Immunology
  1. Ingelfinger, Florian et al. GM-CSF: Master regulator of the T cell-phagocyte interface during inflammation. Science direct Volume 54, April 2021, 101518
  1. Tuzlak, Selma et al. Repositioning TH cell polarization from single cytokines to complex help. Nature immunology vol. 22,10 (2021): 1210-1217.
  1. Becher, B. et al. Skipping adolescence to become super-inflammatory monocytes. Nat Immunol. 21(5):491-492 (2020).
  1. Zwicky, P., Unger, S. & Becher, B. Targeting interleukin-17 in chronic inflammatory disease: A clinical perspective. J. Exp. Med. 217, (2020).
  1. Becher, B., Waisman, A. & Lu, L. F. Cre-lox: Target Sensitivity Matters. Immunity vol. 51 595 (2019).
  1. Mundt, S., Greter, M., Flügel, A. & Becher, B. The CNS Immune Landscape from the Viewpoint of a T Cell. Trends in Neurosciences vol. 42 667–679 (2019).
  1. Tugues, S., Ducimetiere, L., Friebel, E. & Becher, B. Innate lymphoid cells as regulators of the tumor microenvironment. Seminars in Immunology vol. 41 101270 (2019).
  1. Galli, E. et al. The end of omics? High dimensional single cell analysis in precision medicine. European Journal of Immunology vol. 49 212–220 (2019).
  1. Becher, B., Waisman, A. & Lu, L. F. Conditional Gene-Targeting in Mice: Problems and Solutions. Immunity 48, 835–836 (2018).